apalutamide will lower the extent or result of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Steer clear of or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP2C19 inducer, with medications which are CYP2C19 substrates may result in decreased publicity to those prescription drugs.Can I generate or ride a motorbike? Nev